Constructing a one to one correspondence between whole brain MR image scans is a problem of critical importance in neuroimaging analyses. We have developed a framework to combine the strength of both surface-based and volumetric-based analyses for consistent, bijective data transfer between brain coordinate systems.
By combining a good volumetric registration, with a topology preserving projection from one surface to the other, anatomical surfaces can be registered accurately. SAVOR yields registrations with high correlation of cortical biomarkers and little misregitration of cortical parcellation labels. |
